Novel, Specific O-Glycosylation of Secreted Flavobacterium meningosepticum Proteins.
نویسندگان
چکیده
منابع مشابه
Flavobacterium meningosepticum as an opportunist.
Flavobacterium meningosepticum was isolated from the cerebrospinal fluid of an adult immunodeficient female. In spite of prompt therapy the patient succumbed to the infection. The opportunistic role of the organism is discussed.
متن کاملFlavobacterium meningosepticum: an unusual pathogen.
We are reporting the isolation of F. Meningosepticum from the blood culture of a 11⁄2 year old girl. She was a known case of tuberculous meningitis stage III with obstructive hydrocephalus and had undergone shunt surgery. The child was receiving adequate antitubercular treatment along with decongestants and anti-convulsants regularly. Following shunt surgery, the child started running high grad...
متن کاملFlavobacterium meningosepticum in the hospital environment.
Ten strains of Flavobacterium meningosepticum were isolated from routine clinical material during a period of two years. Of a number of antibiotics tested, clindamycin was the only one to which they were fully sensitive. The organism was found in chlorhexidine gluconate (Hibitane) solutions in use on the wards for the storage of thermometers and for routine disinfection.
متن کاملTrimethoprim sulphamethoxazole in neonatal Flavobacterium meningosepticum infection.
During an outbreak of Flavobacterium meningosepticum septicaemia in a neonatal intensive care unit 9 infants were treated with intravenous trimethoprim sulphamethoxazole. Bacteriological cure was achieved in 8 patients; one infant died of massive intraventricular haemorrhage on the first day of treatment. Apart from prolonged persistence of pre-existing thrombocytopenia there was no evidence of...
متن کاملSite-specific O-Glycosylation Analysis of Human Blood Plasma Proteins*
Site-specific glycosylation analysis is key to investigate structure-function relationships of glycoproteins, e.g. in the context of antigenicity and disease progression. The analysis, though, is quite challenging and time consuming, in particular for O-glycosylated proteins. In consequence, despite their clinical and biopharmaceutical importance, many human blood plasma glycoproteins have not ...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1995
ISSN: 0021-9258
DOI: 10.1074/jbc.270.22.13192